What You Need to Know About Medical Aesthetics

Neutralizing antibody is the production of antibodies by the immune system that can reduce the biological effect of botulinum toxin. Verified neutralizing antibody at aesthetic doses is rare; product, dose, storage, preparation, target muscle, time
Botox failing to deliver the expected effect can have several causes: the effect not yet having set in (timing), dose/technique factors, product storage/dilut

When Botox seems weak or absent, the cause may be timing, dilution, dose, storage, anatomy, unrealistic expectations, or rarely antibody resistance.