Profhilo
High-concentration hyaluronic acid improves skin hydration and elasticity. Corrects fine lines and skin quality.
Treatment Information
Duration
20-30 minutes
Body Location
Face, neck, décolletage, hands or selected skin areas after assessment
Preparation
No special preparation is usually needed. Avoid alcohol for 24 hours; do not stop prescribed medication or blood thinners on your own, and disclose them to the physician.
Follow-up Care
Mild swelling may persist 24-48 hours. Use SPF 50+ sunscreen.
How It Is Performed
High-concentration hyaluronic acid injected into mid-dermis. Helps restore skin structure.
HA Filler vs Collagen Stimulator: A Strategic Choice in Facial Rejuvenation
Hyaluronic-acid (HA) fillers may be used for volume or structural support in selected areas. Biostimulators such as PLLA and CaHA differ in onset, intended use, and risk profile; products are not interchangeable. This matrix explains general decision factors and is not an individual treatment recommendation.
| Criterion | Hyaluronic Acid Filler | Collagen Stimulator (PLLA / CaHA) |
|---|---|---|
| Mode of Action | Adds volume directly; visible immediately after injection | Triggers neocollagenesis; result builds gradually over 8–12 weeks |
| Onset of Results | Immediate — same session | Delayed — gradual over 2–3 months |
| Longevity | 9–18 months depending on product and area | Varies by product, area, protocol, and individual response; a fixed duration cannot be promised in advance. |
| Reversible? | Some HA fillers may be reduced with hyaluronidase; complete or immediate reversal should not be assumed. | No — must be metabolised naturally |
| Ideal Area | Lips, cheeks, nasolabial, tear trough, jawline, hands | Broad mid-face volume loss, temples, jowls, décolleté |
| Effect on Tissue Quality | Hydration, volume, or structural support may be targeted depending on product and treatment plan. | Marked — improves skin thickness, firmness, and elasticity |
| Initial Protocol | Individualised according to product, area, amount needed, and tissue response. | Planned by the physician according to product information, area, and individual response. |
| Risk / Side Effect Profile | Mild swelling/bruising; vascular events rare but serious | Nodules, inflammation, infection, and vascular complications can occur; some products cannot be enzymatically reversed. |
| How Is the Fee Determined? | Product, amount, area, technique, and review plan are determined after physician examination. | Product, total amount needed, session plan, and follow-up requirements are determined after examination. |
Dr. Gemici's Recommendation
A localised volume or contour goal may prompt assessment for HA filler, while broader tissue-support goals may prompt assessment for an appropriate biostimulator. Product choice should never be automatic, especially in vascularly sensitive areas such as the tear trough. Reversibility, anatomy, and the complication-management plan should be considered together.
Frequently Asked Questions
No, Profhilo does not immobilize muscles. It focuses more on skin quality and hydration.
Initial results appear after 2-3 weeks. most appropriate results achieved within 2-3 months.
Most patients have sessions every 2-3 months or start with two sessions 2 weeks apart.
Pregnant, nursing, or those with hyaluronic acid allergy are not suitable. Consult if prone to keloids.
Mild swelling and redness persist 24-48 hours. Mild soreness 1-2 days after injection is normal.
Yes, very common. Profhilo provides hydration, Botox addresses dynamic wrinkles, fillers restore volume.
Initial two sessions 2 weeks apart, then maintenance every 3 months. Effect lasts 6-8 months.
Safety and complication management
Profhilo is a safe procedure; still, as with any medical treatment, explaining possible side effects and rare complications transparently is part of patient safety. The physician-authored guides below cover these topics in depth.
- Nodules and delayed-type reactionsEarly vs late nodules, biofilm–granuloma–inflammatory assessment and management steps.
- Which side effect is normal, which is urgent?A triage guide separating expected post-treatment reactions from the red flags that need a physician.
This content is informational and does not replace medical advice. At any warning sign, contact the physician who performed the procedure or the nearest medical facility without delay.
Profhilo — Related Medical Terms
Deep-dive in our glossary: definition, indications, side effects and FAQs.
Hyaluronic Acid
Hyaluronic acid (HA), the active ingredient used in dermal fillers, is a high molecular weight glucosaminoglycan polymer composed of β-1,4-D-glucuronic acid and β-1,3-N-acetyl-D-glucosamine repeating disaccharide, occurring naturally in the body; It is the most commonly used filler in facial filler in aesthetic injections, increasing skin hydration and volumetricity.
Neck Rejuvenation
Against platysmal bands, horizontal wrinkles and pigmentation problems of the neck area; Multimodal aesthetic procedure with a combination of botox, hyaluronic acid, biostimulators and laser.
Décolletage Rejuvenation
Décolletage rejuvenation is a site-specific multimodal procedure applied with the combination of IPL, hyaluronic acid skinbooster, fractional laser and topical retinol to eliminate poikiloderma (hyperpigmentation + telangiectasia + atrophy), horizontal wrinkles and crepey skin occurring in the V-neck area (under the clavicle - sternum - upper chest).
Hand Rejuvenation
Hand rejuvenation is a procedure to treat thin skin, tortuous veins, sun damage pigmentation (lentigines) and volume loss of the dorsum manus (back of the hand) with a combination of HA filler, Radiesse biostimulation, laser (IPL/Q-switched NdYag) and topical retinol.
Filler
Filler; They are biocompatible materials that are injected into selected areas of the face, restore volume loss, fill static lines and improve facial contour, and have varieties such as hyaluronic acid, calcium hydroxyapatite, poly-L-lactic acid and autologous oil.
Jawline Contour
Jawline contour; An aesthetic technique that shapes the mandibular edge line (ramus, gonion, chin tip) with a combination of CaHA/HA filler and masseter Botox, providing lower facial proportions, sharp definition in men, and elegant taper in women.
Niacinamide
Niacinamide (nicotinamide) is the amide form of Vitamin B3 and is the active ingredient in cosmeceutical serums that strengthens the skin barrier, provides sebum regulation, inhibits melanin transfer and supports collagen synthesis; As a NAD+/NADP+ precursor, it is active in cellular energy metabolism.
Peptide Serum
Peptide serum are cosmeceutical active substances consisting of short-chain amino acid sequences (typically 2-50 amino acids, mostly 3-6), which trigger collagen and elastin synthesis, inhibit neurotransmitter release or prevent enzymatic degradation; They form the main component of the bulk in topical serum formulations used against signs of aging (wrinkles, loss of skin tension, fine lines).
humidifier
Moisturizer is a topical product that reduces the skin's trans-epidermal water loss (TEWL) and supports the skin barrier; It is a daily skin care product that should be selected and applied according to skin type, in lotion/cream/balm/ointment format, divided into three basic component categories: occlusive (prevent water loss), humectant (absorb water) and emollient (soften).
Sources & Regulatory Authorities
Information sourced from official regulatory authority databases (FDA, EMA, TİTCK) and peer-reviewed medical literature. Not a substitute for medical advice; clinical decisions are always individualized.
Product Approvals (FDA / EMA / TİTCK)
- CE
- TİTCK
Scientific References (PubMed / Cochrane)
- Sparavigna A, Tenconi B, La Penna L. A new hyaluronic acid product for the treatment of skin laxity (BAP technique) · J Cosmet Dermatol (2017)
- Cassuto D, Bellia G, Schiraldi C. Stabilized hyaluronic acid hybrid complex for facial bioremodeling · Clin Cosmet Investig Dermatol (2021)
Related Services
Plan an Assessment
Contact Dr. Hamza Gemici’s clinic for individualized assessment and candidacy planning.