HA cross-linking
Hyaluronic acid in its natural state is liquid and breaks down rapidly (a few hours) in the body. For it to be used as a filler, the molecules are linked together by cross-links. The intensity and type of this cross-linking determine the hardness of the filler and how long it will remain under the skin.
Juvederm family (Allergan)
Juvederm Ultra 3, Ultra 4: medium-density, for lips and nasolabial folds.
Juvederm Volbella: softest, for fine lips and tear troughs.
Juvederm Volift: medium deep; for mid-face, fine lines.
Juvederm Voluma: firm, deep; for cheek and chin support.
Juvederm Volux: firmest; for jawline and chin recontouring.
Restylane family (Galderma)
Restylane Kysse: developed for lip features; preserves natural movement.
Restylane Defyne, Refyne: "bends with you" feature in mimicry; for nasolabial and marionette lines.
Restylane Lyft: firm; for cheekbone and bone support.
Restylane Vital, Skinboosters: non-cross-linked; for skin quality.
Teosyal (Teoxane, Switzerland) and Belotero (Merz)
Teosyal RHA series: Dynamic Resilience technology — compatible with mimicry, preserves natural movement.
Belotero Balance, Soft, Intense: transition from soft to firm; from superficial lines to medium deep.
Belotero Volume, Revive: for deep volume and skin quality.
Attention:There are fillers sold as "permanent" or "semi-permanent" on the market (silicone, PMMA). These are irreversible products with a high risk of granuloma and chronic inflammation. They are banned in most European countries. Only HA-based, reversible fillers should be used.
Deep fillers (cheekbone, chin)
- Juvederm Voluma, Volux
- Restylane Lyft
- Teosyal Ultra Deep
- Belotero Volume
Soft fillers (lips, tear trough)
- Juvederm Volbella, Ultra
- Restylane Kysse, Defyne
- Teosyal RHA 2, 3
- Belotero Balance, Soft
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Neck and Decollete: The Extended Architecture of the Face